Welcome to the EuPA website!
EuPA is the federation of European national proteomics societies. It has been established to coordinate and integrate national initiatives within the proteomics field. The main objectives are to strengthen and promote fundamental research and applications, through education and training in all areas of proteomics throughout Europe. EuPA is a non-profit organisation.
EuPA Open Proteomics
... is the official owned journal of the European Proteomics Association (EuPA) and is aimed at both European and international protein scientists.
EuPA Open Proteomics is an open access journal and was launched autumn 2012.
Editor in Chief: Peter Verhaert, Delft University of Technology, Delft, Netherlands
EUPA 2013 conference and extended deadlines
4 months to go before EuPA 2013´s opening and yet:
400 registered attendees
300 communications submitted
Don't miss out on a great opportunity to attend:
- Abstract submission deadline extended to June 24 at 20:00 GMT
- Early bird registration rates extended to July 31 included
- New trade exhibition spaces added
Postdoctoral researcher in ‘Mass Spectrometry based Functional Proteomics’
Location: Odense, Denmark
A post doctoral position is available in the research group of Associate Professor Blagoy Blagoev at the Department of Biochemistry and Molecular Biology, University of Southern Denmark, Odense. The position is for one or two years with a possibility for extension.
The qualified applicant holds a PhD degree and documented background in protein biochemistry. Hands-on training with protein mass spectrometry as well as experience with computational data analysis are compulsory. Experience with Orbitrap mass spectrometers and SILAC labelling will be ideal.
We seek a highly motivated individual with a strong scientific background and track-record in mass spectrometry-based proteomics. Experience with large-scale analysis of post-translational modifications would be of further advantage. The successful applicant will primarily use quantitative proteomic approaches to study post-translational modifications such as phosphorylation and ubiquitination, in regard to regulation of mammalian signalling networks.
The position focuses mainly on successfully funded projects, without excluding the possibility of the candidates to work on additional research projects of interest.
Application open until: 2013-06-31
Please see the full call, including how to apply, on www.sdu.dk
PhD position in cancer proteomics and molecular biology : 81377 München, Germany
Location: Munich, Germany
PhD position in cancer proteomics and molecular biology
Department of neuroproteomics of the Technische Universität Munich (TUM)
Dr. Dr. med. Peer-Hendrik Kuhn, Prof. Dr. Stefan F. Lichtenthaler
The secretome, the entity of all secreted or proteolytically liberated proteins from a cell can undergo disease specific changes. Therefore the secretome is a resource for disease specific biomarkers. The project aims at the identification of disease specific changes of the secretome in acute myeloid leukemia (AML). These results will aid a better understanding of AML biology and the development of novel biomarker tests that later help physicians in therapy decisions for AML patients.
Besides mass spectrometry and secretome protein enrichment with click sugars (SPECS) technology the project involves the use of standard protein biochemistry and molecular biology techniques like cloning, protein expression, cell culture, Western blot, immunofluorescence and ELISA. Furthermore the candidate is expected to develop or improve methods currently running in the lab after a certain time of close supervision.
We provide a clear research topic as well as excellent training and support of a PhD student in order to develop his personal talents and interests within framework of the Institute of Advanced Studies of Technische Universität Munich. Payscale is 75% of TV-L E13.
You should have a strong background and interest in molecular, cellular biology as well as practical experience in molecular biology or cell biology – gained for example during your master’s thesis. Experience with DNA cloning, tissue culture or Western Blots would be preferred. An interest for mass spectrometry and method development for solving complex biological questions would be desirable.
Proteomics based analysis of RNA virus entry and exit : Birmingham, United Kingdom
Location: Birmingham, UK
Closing date: Applications are invited until the position has been filled.
Project title: Proteomics based analysis of RNA virus entry and exit
Lead supervisor: Dr Dalan Bailey
Second Supervisor: Professor Jane McKeating
Institute: University of Birmingham, School of Immunity and Infection, College of Medical and Dental Sciences
Paramyxoviruses are a great health and economic burden across the globe resulting in numerous deaths and considerable hardship. Examples from this large family include the well-known human pathogens measles virus (MeV) and respiratory syncytial virus (RSV). These two viruses alone cause a huge number of outbreaks and fatalities each year in the developing world. This family also contains many important viruses of animals as well as dangerous zoonotic pathogens, such as Nipah and Hendra virus.
Paramyxoviruses such as MeV and RSV are enveloped and acquire their membrane from infected cells in a process known as budding. This envelope then fuses with the target cell after attachment to allow the viral genome into the cell. Unfortunately, the interactions involved in both these processes are not fully understood. The aim of this PhD project is therefore to significantly improve our understanding and knowledge of these viral mechanisms. This information can then be used for the rational design of antivirals and vaccines in the future.
This project adopts a multidisciplinary approach to the study of viral entry and exit, leveraging new methods in proteomics, bioinformatics and systems biology to gain a fundamental understanding of the mechanisms involved. The project will focus on applying proteomics technology (such as quantitative proteomics, tandem affinity purification and mass spectrometry) and bioinformatics (mapping and analysing interaction networks) to dissect the mechanisms of virus attachment and release. Small RNA viruses frequently hijack components of the cell in order to drive the production of new virus particles. Isolating, identifying and characterising this hijacked host cell machinery in the context of infected cells will provide the chosen student with the unique opportunity to work with important human pathogens and develop the key virology skills required for a career in research.
In addition to proteomics and bioinformatics, this project will involve the use of confocal and electron microscopy, quantitative PCR, cloning and reverse genetics. The application of these techniques to negative strand RNA viruses represents an exciting and novel area for future research. As such the targets of this project are the publication of peer-reviewed publications in high-impact journals as well as the presentation of data, by the student, at national and international conferences.
Essential: A keen interest in virology and/or systems biology as well as a commitment to research. Applicants should hold, or realistically expect to obtain, at least an Upper Second Class Honours Degree in a relevant subject.
Desirable: Applicants should have a strong background in protein biochemistry/cell/molecular biology. Previous laboratory experience is also desirable, although full training will be provided.
Funding and eligibility:
This position is fully funded for University fees and a stipend at standard Research Council UK rates and, due to the funding, is open for applications from UK and EU applicants.
How to apply
Interviews will take place early July with the position commencing October 2013.
Post Doc Researcher in Epigenetics and Proteomics : Grenoble, France
Employer: CEA Grenoble
Location: Grenoble, France
SCIENTIFIC ENVIRONMENT The Research Group « Exploring the Dynamics of Proteomes » (EDyP) develops a variety of proteomic approaches within large scale projects, with biological and/or clinical perspectives. Our expertise is used to tackle a number of innovative questions in cell biology, plant physiology and medical sciences. SCIENTIFIC PROJECTS You will be part of a new research program, lead by Jerome Govin. We are investigating epigenetics and chromatin dynamics during the differentiation of gametes. We are using a model organism, the yeast Saccharomyces cerevisiae, which has been proven to be an efficient way to rapidly reveal new aspects of the chromatin dynamics in gametes .
YOUR MISSION You will be in charge of developing several aspects of EpiGam. More precisely, you will study the dynamics of chromatin during gamete differentiation using the yeast S. cerevisiae. You will focus on the functions of chromatin proteins / histones during the post meiotic differentiation of yeast spores. You will also be involved in: - Plan and develop the experimental plan. It will involve biochemistry and proteomics. - Participate in the usual lab routine (orders, lab jobs,) - Actively contribute to the dissemination of the results (meetings, publications in peer-reviewed journals) YOUR EXPERTISE You have a PhD in Life Sciences. Your publication track attests your expertise in your field in biology and/or mass spectrometry. You will be in charge proteomics analysis : (i) discovery proteomics including biochemistry, MS analysis and data processing. (ii) middle-down and top-down analyses using high resolution MS. You are able to develop your experimental plan independently, and to work efficiently in a team. You have excellent relational and organizational abilities. You are used to written and oral communication in English.
Following the usual French benefits. Please contact us for more informations.
Application open until: 2013-06-19
PhD position in Molecular Biology - Quantitative proteomics : Mainz, Germany
Location: Mainz, Germany
In the field of “Quantitative proteomics in telomere biology and long non-coding RNA regulation” the research group of Dr. Falk Butter offers the following PhD project: Characterization of a novel telomere-binding protein
We developed an approach to identify transcription factors binding to functional DNA elements using SILAC-based quantitative mass spectrometry (Mittler et al., 2009; Butter et al., 2012). Recently, we applied this technique to study proteins binding to the telomeric repeat motif and identified a novel direct telomere binding protein (unpublished data). Telomeres, the protective cap of chromosomes, are implicated in various biological processes such as ageing and cancer development. In normal differentiated cells, telomeres gradually shorten with cell divisions, defining the proliferative capacity and ultimately inducing cellular senescence. However, in stem and cancer cells this mechanism is counteracted by de novo addition of telomeric repeats. Thus, a detailed and comprehensive understanding of telomere regulation is of fundamental importance for our understanding of cell development, cancer and ageing. The discovery-oriented PhD project aims to characterize the function and mechanism of the novel telomere binding protein. We seek a motivated teammate interested in combining state-of-the art systems level technologies (transcriptomics, proteomics, ChIP-seq) with classical biochemical and cell biological techniques. The work will involve a variety of techniques, ranging from protein purification and in vitro assays to RNA interference, in situ staining and reporter gene assays in mammalian cell culture as well as the investigation of a future mouse model. We offer • The possibility to work on a cutting-edge project using state-of-the-art technology in a highly motivated research team • A stimulating, diverse and international research environment • Advanced training opportunities • A competitive stipend Required qualifications • Master or Diploma • Motivation to solve complex biological problems • Excellent communication skills Starting date: 1 October 2013 or later Duration of stipend: 3 years, with the possibility of extension Deadline for applications (exclusively online via web form): 1 July 2013
Application open until: 2013-07-01
Additional information: http://www.imb-mainz.de/PhD
Proteomics and Metabolomics Postdoc (m/f) : Leiden, Netherlands
Employer: Leiden University Medical Center
Location: Leiden, Netherlands
As a postdoc in the Center for Proteomics and Metabolomics you will join a leading team in clinical imaging mass spectrometry. You will develop new capabilities for quantitative and validated imaging mass spectrometry analyses and apply these novel tools to soft-tissue sarcomas. In this manner imaging mass spectrometry, complemented by the analysis of microdissected samples, will be used to investigate the biomolecular intratumor heterogeneity in these complex tumors, thereby revealing the biomolecular changes accompanying tumor progression and providing improved diagnostic capabilities. The project is a collaboration with the Department of Pathology (LUMC). You will join leading experts in imaging mass spectrometry, clinical mass spectrometry and soft tissue sarcoma pathology; and use class leading biomolecular techniques in molecular imaging and biomolecular analysis.
You have a PhD in Biomolecular mass spectrometry or Bioinformatics and an excellent command of the English language, since you will be expected to present and publish your results at international workshops and conferences. A flexible work approach is essential, as well as the ability to work effectively within an international, multidisciplinary team. Above all, you are enthusiastic and ambitious.
You will be employed on the basis of a 36-hour week. Appointment is temporary with a maximum of 3 years. Your salary will depend on your qualifications and experience, with a maximum of € 3.961 gross per month based on a 36-hour week (scale 10, CAO UMC). The terms of employment offered by the LUMC are highly favourable. For example, you will receive an 8% holiday remuneration, a year-end bonus, a pension arrangement with the National Civil Pension Fund, and, if applicable, a bonus for unsocial hours. Also, as employee of one of the University Hospitals in the Netherlands, you will naturally join our collective health insurance policy. Moreover, the LUMC offers excellent facilities in the area of education, child-care centres, and career advice. In addition, you may enjoy various leave arrangements and other extras.
Application open until: 2013-07-01
Clinical Proteomics : Hannover, Germany
Employer: Mosaiques Diagnostics GmbH
Location: Hannover, Germany
Two positions at the junior and senior postdoc level are available at Mosaiques Diagnostics in Hannover, GERMANY. The projects involve employing capillary electrophoresisi coupled mass spectrometry for the identification and validation of proteomic biomarkers for a variety of human diseases, with a focus on cardiovascular and kidney disease. Mosaiques Diagnostics is a leading company in proteomic biomarker research, focusing on urine. Further information on the technology and application is detailed in e.g.; Good et al. Mol. Cell Proteomics 2010, 9:2424; Mischak et al. Proteomics Clin. Appl. 2011, 5:9; Mullen et al. Curr. Opin. Nephrol. Hypertens. 2011, 20:654; Kuznetsova et al. Eur. Heart J 2012 33: 2342; Zürbig et al. Diabetes 2012 61:3304-3313; Metzger et al., Gut. 2013 62:122; Stalmach et al., Electrophoresis, in press.
The project requires close interaction with collaborating scientists and clinicians in and outside Germany, e.g. the U.K., Denmark, Austria, France, Greece, US, and Australia.
Candidates are requested to hold a PhD in (bio)chemistry or relevant fields and have expertise in mass spectrometry. English proficiency is required.
The ideal candidate for the junior position should have a track record of publications in the proteomics field. The ideal candidate for the senior position should be well established in the field, have experience in clinical studies, and experience in attracting funding including EU applications.
The positions are in a fast moving SME Biomarker research and development company and would suite someone with ambition and a drive to succeed. Additional experience in “omics” technology, separation science and data handling is desirable, but not mandatory.
Salary is negotiable, depending on experience. The position is open-ended.
Application open until: 2013-06-30
Proteomics Postdoc m/v
Employer: Leiden University Medical Centre (LUMC)
Location: Leiden, The Netherlands
Would you, as a post doc, like to join our leading experts in mass spectrometry? In our Center for Proteomics and Metabolomics you will develop new capabilities for quantitative and validated imaging mass spectrometry analyses and apply these novel tools to soft-tissue sarcomas. The project is a collaboration with the Department of Pathology (LUMC). You will join leading experts in imaging mass spectrometry, clinical mass spectrometry and soft tissue sarcoma pathology; and use class leading biomolecular techniques in molecular imaging and biomolecular analysis.
Contact: A detailed job description can be found at www.lumc.nl/vacancies. You may also contact dr. Liam McDonnel, associate professor, Center for Proteomics and Metabolomics, phone+31 71 526 8744.
Application open until: 01-07-2013
Upcoming Educational Activities and Conferences
|Sun Jun 23, 2013 @08:00 - 05:00PM|
Summer School on Computational Mass Spectrometry- Based Proteomics
|Thu Jun 27, 2013 @08:00 - 05:00PM|
MALDI imaging hands on training
|Mon Jul 01, 2013 @08:00 - 05:00PM|
Basic course: Electrophoresis for Proteomics
|Wed Jul 03, 2013 @08:00 - 05:00PM|
1st international AUPA computational proteomics workshop
|Sun Jul 07, 2013 @08:00 - 05:00PM|
Mass spectrometry in biotechnology & medicine summer school
|Mon Jul 15, 2013 @08:00 - 05:00PM|
SRM Course ETH Zürich
|Fri Jul 19, 2013 @08:00 - 05:00PM|
Mass Spectrometry workshop at ISMB/ECCB
|Thu Jul 25, 2013 @08:00 - 05:00PM|
UPCP 2013 – Up Close and Personalized – The 2nd International Congress on Personalized Medicine
|Sun Aug 04, 2013 @08:00 - 05:00PM|
7th European Summer School "ADVANCED PROTEOMICS"
|Thu Aug 08, 2013|
Protein Interactions and Networks Lab Course